What is Atopic Dermatitis?

The absence of filaggrin (black specks on the microphotographs)

is a major factor in the onset of atopic dermatitis.

(excerpt from the Journal of Investigative Dermatology)

Filaggrin staining

in normal skin

Ichthyosis vulgaris

and atopic dermatitis

Normal skin barrier

Fillagrin granules

Defective skin barrier

No filaggrin granules

Normal skin

Skin deficient in filaggrin

and abnormally permeable